Questa sezione contiene la lista delle pubblicazioni (libri, brochure informative, report, articoli, etc..) realizzati nell'ambito del Centro e dei suoi Istituti Membri
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NatSynDrugs
Centro Interuniversitario per la Progettazione e lo Sviluppo dei Farmaci
- Nathwani, S. M.; Butler, S.; Meegan, M. J.; Campiani, G.; Lawler, M.; Williams, D. C.; Zisterer, D. M. Dual targeting of tumour cells and host endothelial cells by novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines. Cancer Chemother Pharmacol 2009
- Morelli, E.; Gemma, S.; Budriesi, R.; Campiani, G.; Novellino, E.; Fattorusso, C.; Catalanotti, B.; Coccone, S. S.; Ros, S.; Borrelli, G.; Persico, M.; Fiorini, I.; Nacci, V.; Ioan, P.; Chiarini, A.; Hamon, M.; Cagnotto, A.; Mennini, T.; Fracasso, C.; Colovic, M.; Caccia, S.; Butini, S. Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships. J Med Chem 2009, 52, 3548-62
- McElligott, A. M.; Maginn, E. N.; Greene, L. M.; McGuckin, S.; Hayat, A.; Browne, P. V.; Butini, S.; Campiani, G.; Catherwood, M. A.; Vandenberghe, E.; Williams, D. C.; Zisterer, D. M.; Lawler, M. The Novel Tubulin-Targeting Agent Pyrrolo-1,5-Benzoxazepine-15 Induces Apoptosis in Poor Prognostic Subgroups of Chronic Lymphocytic Leukemia. Cancer Res 2009
- Gemma, S.; Savini, L.; Altarelli, M.; Tripaldi, P.; Chiasserini, L.; Coccone, S. S.; Kumar, V.; Camodeca, C.; Campiani, G.; Novellino, E.; Clarizio, S.; Delogu, G.; Butini, S. Development of antitubercular compounds based on a 4-quinolylhydrazone scaffold. Further structure-activity relationship studies. Bioorg Med Chem 2009, 17, 6063-72
- Gemma, S.; Campiani, G.; Butini, S.; Joshi, B. P.; Kukreja, G.; Coccone, S. S.; Bernetti, M.; Persico, M.; Nacci, V.; Fiorini, I.; Novellino, E.; Taramelli, D.; Basilico, N.; Parapini, S.; Yardley, V.; Croft, S.; Keller-Maerki, S.; Rottmann, M.; Brun, R.; Coletta, M.; Marini, S.; Guiso, G.; Caccia, S.; Fattorusso, C. Combining 4-Aminoquinoline- and Clotrimazole-Based Pharmacophores toward Innovative and Potent Hybrid Antimalarials. Journal of Medicinal Chemistry 2009, 52, 502-513
- Ferlini, C.; Cicchillitti, L.; Raspaglio, G.; Bartollino, S.; Cimitan, S.; Bertucci, C.; Mozzetti, S.; Gallo, D.; Persico, M.; Fattorusso, C.; Campiani, G.; Scambia, G. Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77. Cancer Res 2009, 69, 6906-14
- Butini, S.; Gemma, S.; Campiani, G.; Franceschini, S.; Trotta, F.; Borriello, M.; Ceres, N.; Ros, S.; Coccone, S. S.; Bernetti, M.; De Angelis, M.; Brindisi, M.; Nacci, V.; Fiorini, I.; Novellino, E.; Cagnotto, A.; Mennini, T.; Sandager-Nielsen, K.; Andreasen, J. T.; Scheel-Kruger, J.; Mikkelsen, J. D.; Fattorusso, C. Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior. J Med Chem 2009, 52, 151-69
- Butini, S.; Budriesi, R.; Hamon, M.; Morelli, E.; Gemma, S.; Brindisi, M.; Borrelli, G.; Novellino, E.; Fiorini, I.; Ioan, P.; Chiarini, A.; Cagnotto, A.; Mennini, T.; Fracasso, C.; Caccia, S.; Campiani, G. Novel, Potent, and Selective Quinoxaline-Based 5-HT(3) Receptor Ligands. 1. Further Structure-Activity Relationships and Pharmacological Characterization. J Med Chem 2009
- Butini, S.; Brindisi, M.; Cosconati, S.; Marinelli, L.; Borrelli, G.; Coccone, S. S.; Ramunno, A.; Campiani, G.; Novellino, E.; Zanoli, S.; Samuele, A.; Giorgi, G.; Bergamini, A.; Di Mattia, M.; Lalli, S.; Galletti, B.; Gemma, S.; Maga, G. Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations. Journal of Medicinal Chemistry 2009, 52, 1224-1228.
- Bright, S. A.; Greene, L. M.; Greene, T. F.; Campiani, G.; Butini, S.; Brindisi, M.; Lawler, M.; Meegan, M. J.; Williams, D. C.; Zisterer, D. M. The novel pyrrolo-1,5-benzoxazepine, PBOX-21, potentiates the apoptotic efficacy of STI571 (imatinib mesylate) in human chronic myeloid leukaemia cells. Biochemical Pharmacology 2009, 77, 310-321
- Bane, F. T.; Bannon, J. H.; Pennington, S. R.; Campiani, G.; Williams, D. C.; Zisterer, D. M.; Mc Gee, M. M. The microtubule-targeting agents, PBOX-6 and paclitaxel, induce nuclear-cytoplasmic redistribution of the peptidyl prolyl isomerases, cyclophilin A and pin1, in malignant haematopoietic cells. J Pharmacol Exp Ther 2009
- S. Zanoli, S. Gemma, S. Butini, M. Brindisi, B. P. Joshi, G. Campiani, C. Fattorusso, M. Persico, E. Crespan, R. Cancio, S. Spadari, U. Hubscher, G. Maga - 'Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the "primer grip" region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants. '
Biochemical Pharmacology 2008, 76, 156-168
- M. Stasi, S. Di Serio, M. Vertechy, A. Schiavone, O. Ghirardi, P. Minetti, G. Campiani, F. Borsini, P. Carminati -'ST2472: a new potential antipsychotic with very low liability to induce side-effects. '
International Journal of Neuropsychopharmacology 2008, Vol.11, 309 - 319
- S. Gemma, G. Kukreja, P. Tripaldi, M. Altarelli, M. Bernetti, S. Franceschini, L. Savini, G. Campiani, C. Fattorusso, S. Butini - 'Microwave-assisted synthesis of 4-quinolylhydrazines followed by nickel boridereduction: a convenient approach to 4-aminoquinolines and derivatives '
TETRAHEDRON LETTERS 2008, Vol.49, 2074 - 2077
- S. Butini, G. Campiani, M. Borriello, S. Gemma, A. Panico, M. Persico, Catalanotti Bruno, S. Ros, M. Brindisi, M. Agnusdei, I. Fiorini, V. Nacci, E. Novellino, T. Belinskaya, Saxena Ashima, Fattorusso Caterina - 'Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent Inhibitors.' (pubblicazione su rivista, 2008) J Med Chem; in corso di stampa (lettera di accettazione del 15-05-2008)
- N. Verma, E. Dempsey, J. Conroy, P. Olwell, A. M. Mcelligott, A. M. Davies, D. Kelleher, S. Butini, G. Campiani, D. Williams, D. M. Zisterer, M. Lawler, Y. Volkov- 'A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin.'
J. Mol Med 2008, Vol.86, 457 - 469
- Sandra Gemma, Giuseppe Campiani, Stefania Butini, Gagan Kukreja, Salvatore Sanna Coccone, Bhupendra P. Joshi, Marco Persico, Vito Nacci, Isabella Fiorini, Ettore Novellino, Ernesto Fattorusso, Orazio Taglialatela-Scafati, Luisa Savini, Donatella Taramelli, Nicoletta Basilico, Silvia Parapini, Giulia Morace, Vanessa Yardley, Simon Croft, Massimiliano Coletta, Stefano Marini, and Caterina Fattorusso
Clotrimazole Scaffold as an Innovative Pharmacophore Towards Potent Antimalarial Agents: Design, Synthesis, and Biological and Structure–Activity Relationship Studies
J. Med. Chem., 2008, 51 (5), 1278–1294
- Caterina Fattorusso, Giuseppe Campiani, Gagan Kukreja, Marco Persico, Stefania Butini, Maria Pia Romano, Maria Altarelli, Sindu Ros, Margherita Brindisi, Luisa Savini, Ettore Novellino, Vito Nacci, Ernesto Fattorusso, Silvia Parapini, Nicoletta Basilico, Donatella Taramelli, Vanessa Yardley, Simon Croft, Marianna Borriello, and Sandra Gemma
Design, Synthesis, and Structure–Activity Relationship Studies of 4-Quinolinyl- and 9-Acrydinylhydrazones as Potent Antimalarial Agents
J. Med. Chem., 2008, 51 (5, 1333–1343.
- Greene LM, Campiani G, Lawler M, Williams DC, Zisterer DM.
BubR1 Is Required for a Sustained Mitotic Spindle Checkpoint Arrest in Human Cancer Cells Treated with Tubulin-Targeting Pyrrolo-1,5-Benzoxazepines
Mol Pharmacol., 2008, 73(2), 419-430.
- Stasi MA, Di Serio S, Vertechy M, Schiavone A, Ghirardi O, Minetti P, Campiani G, Borsini F, Carminati
ST2472: a new potential antipsychotic with very low liability to induce side-effects
Int J Neuropsychopharmacol., 2007, Epub ahead of print , 1-11.
- Campiani, G.; Fattorusso, C.; Butini, S.; Gemma, S.; Sanna Coccone, S.; Borriello, M.
Compounds active on glutamatergic receptors
EP2007/059721, 2007.
- Campiani G, Butini S, Fattorusso C, Franceschini S, Thale ZI, Nielsen KS, Scheel-Krüger J and Madsen LS.
Novel compounds active on dopamine and serotonin receptors.
PCT/EP2007/060888., 2007.
- Gemma S, Campiani G, Butini S, Kukreja G, Joshi BP, Persico M, Catalanotti B, Novellino E, Fattorusso E, Nacci V, Savini L, Taramelli D, Basilico N, Morace G, Yardley V, Fattorusso C.
Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: exploring an innovative pharmacophore.
J Med Chem. , 2007, 50(4) ,595-598.
- Gemma S, Kukreja G, Campiani G, Butini S, Bernetti M, Joshi BP, Savini L, Basilico N, Taramelli D, Yardley V, Bertamino A, Novellino E, Persico M, Catalanotti B, Fattorusso C.
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling.
Bioorg Med Chem Lett., 2007, 17(13), 3535-3539.
- Greene LM, Kelly L, Onnis V, Campiani G, Lawler M, Williams DC, Zisterer DM.
STI-571 (imatinib mesylate) enhances the apoptotic efficacy of pyrrolo-1,5-benzoxazepine-6, a novel microtubule-targeting agent, in both STI-571-sensitive and -resistant Bcr-Abl-positive human chronic myeloid leukemia cells.
J Pharmacol Exp Ther., 2007, 321(1), 288-97.
- Campiani G, Butini S, Fattorusso C, Trotta F, Franceschini S, De Angelis M, Nielsen KS.
Aryl piperazine derivatives for the treatment of neuropsychiatric disorders.
WO 2006/072608., 2006.
- G. Kukreja, G. Campiani, J.M. Khurana, B.P. Joshi, S.K. Grover.
Unexpected formation of hydroxybiphenylmethane derivatives and some new observations on Labat test.
Nat Prod Res., 2006, 20, 1150-1154.
- C. Fattorusso, G. Campiani, B. Catalanotti, M. Persico, N. Basilico, S. Parapini, D. Taramelli, C. Campagnuolo, E. Fattorusso, A. Romano, O. Taglialatela-Scafati.
Endoperoxide derivatives from marine organisms: 1,2-dioxanes of the plakortin family as novel antimalarial agents.
J Med Chem., 2006, 49, 7088-7094.
- S. Gemma, G. Kukreja, C. Fattorusso, M. Persico, M.P. Romano, M. Altarelli, L. Savini, G. Campiani, E. Fattorusso, N. Basilico, D. Taramelli, V. Yardley, S. Butini.
Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains.
Bioorg Med Chem Lett., 2006, 16, 5384-5388.
- L.B. McGrath, V. Onnis, G. Campiani, D.C. Williams, D.M. Zisterer, M.M. Mc Gee.
Caspase-activated DNase (CAD)-independent oligonucleosomal DNA fragmentation in chronic myeloid leukaemia cells; a requirement for serine protease and Mn2+-dependent acidic endonuclease activity.
Apoptosis., 2006, 11, 1473-1487.
- S. Gemma, E. Gabellieri, P. Huleatt, C. Fattorusso, M. Borriello, B. Catalanotti, S. Butini, M. De Angelis, E. Novellino, V. Nacci, T. Belinskaya, A. Saxena, G. Campiani.
Discovery of huperzine A-tacrine hybrids as potent inhibitors of human cholinesterases targeting their midgorge recognition sites.
J Med Chem., 2006, 49, 3421-3425.
- J.P. Colletier, B. Sanson, F. Nachon, E. Gabellieri, C. Fattorusso, G. Campiani, M. Weik. .;
Conformational flexibility in the peripheral site of Torpedo californica acetylcholinesterase revealed by the complex structure with a bifunctional inhibitor.
J Am Chem Soc., 2006, 128, 4526-4527.
- J.M. Mulligan, L.M. Greene, Cloonan S, M.M. Mc Gee, V. Onnis, G. Campiani, C. Fattorusso, M. Lawler, D.C. Williams, D.M. Zisterer.
Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines.
Mol Pharmacol., 2006, 70, 60-70.
- L.M. Greene, M. Fleeton, J. Mulligan, C. Gowda, B.J. Sheahan, G.J. Atkins, G. Campiani, V. Nacci, M. Lawler, D.C. Williams, D.M. Zisterer. .;
The pyrrolo-1,5-benzoxazepine, PBOX-6, inhibits the growth of breast cancer cells in vitro independent of estrogen receptor status and inhibits breast tumour growth in vivo.
Oncol Rep., 2005, 14, 1357-1363.
- Fattorusso, C.; Gemma, S.; Butini, S.; Huleatt, P.; Catalanotti, B.; Persico, M.; De Angelis, M.; Fiorini, I.; Nacci, V.; Ramunno, A.; Rodriquez, M.; Greco, G.; Novellino, E.; Bergamini, A.; Marini, S.; Coletta, M.; Maga, G.; Spadari, S.; Campiani, G.;
Development of Molecular Probes for the Identification of Extra Interaction Sites in the Mid-Gorge and Peripheral Sites of Butyrylcholinesterase (BuChE). Rational Design of Novel, Selective, and Highly Potent BuChE Inhibitors
J. Med. Chem., 2005, 48, 1919 - 1929.
- Ferlini C., Raspaglio G., Mozzetti S., Cicchillitti L. , Filippetti F., Gallo D., Fattorusso C., Campiani G. and Scambia G.
The Seco-Taxane IDN5390 Is Able to Target Class III Beta-Tubulin and to Overcome Paclitaxel Resistance
Cancer Research, 2005, 65, 2397-2405.
- G. Maga, S. Gemma, C. Fattorusso, G. A. Locatelli, S. Butini, M. Persico, G. Kukreja, M. P. Romano, L. Chiasserini, L. Savini, E. Novellino, V. Nacci, S. Spadari e G. Campiani.
Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663
Biochemistry, 2005, 44, 9637-9644.
- M.M. Mc Gee, S. Gemma, S. Butini, A. Ramunno, D.M. Zisterer, C. Fattorusso, B. Catalanotti, G. Kukreja, I. Fiorini, C. Pisano, C. Cucco, E. Novellino, V. Nacci, C.D. Williams, G. Campiani.
Development of Novel and Potent Atypical Antipsychotic Agents: Rational Design, an Efficient Palladium-catalysed Route and Pharmacological Studies
J. Med. Chem., 2005, 48, 1705-1708.
- D.G. Lloyd, R.B. Hughes, D.M. Zisterer, D.C. Williams, C. Fattorusso, B. Catalanotti, M.J. Meegan
Bezoxepin-Derived Estrogen Receptors Modulators: A novel Molecular Scaffold for the Estrogen Receptor
J. Med. Chem., 2004, 47, 5612-5615
- M.M. Mc Gee, L.M Greene, S. Ledwidge, G. Campiani, V. Nacci, M. Lawler, D.C. Williams, D.M Zisterer.
Selective Induction of Apoptosis by PBOX-6 in Leukemia Cells occurs via the JNK Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL
J. Pharmacol. Exp. Ther., 2004, 310, 1084-1095
- G.A. Locatelli, G. Campiani, R. Cancio, E. Morelli, A. Ramunno, S. Gemma, U. Hubscher, S. Spadai, G. Maga
Effects of Drug Resistance Mutations L100I and V106A on the Binding to Pyrrolobenzoxazepinone Nonnucleosisde Inhibitors to the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Catalytic Complex
Antimicrob. Agents Chemother., 2004, 48 1570-1580.
- Cappelli, G. Giuliani, G. Pericot Mohr, A. Gallelli, M. Anzini, S. Vomero, A. Cupello, S. Scarrone, M. Matarrese, R. M. Moresco, F. Fazio, F. Finetti, L. Morbidelli, M. Ziche; A
Nonpeptide NK1 Receptor Agonist Showing Subpicomolar Affinity
J. Med. Chem., 2004, 47, 1315-1318.
- Cappelli A, Pericot Mohr Gl G, Gallelli A, Rizzo M, Anzini M, Vomero S, Mennini L, Ferrari F, Makovec F, Menziani MC, De Benedetti PG, Giorgi G.
Design, Synthesis, Structural Studies, Biological Evaluation, and Computational Simulations of Novel Potent AT1 Angiotensin II Receptor Antagonists Based on the 4-Phenylquinoline Structure
J. Med. Chem., 2004, 47, 2574-86.
- G. Appendino, F. Bianchi, A. Bader, C. Campagnuolo, E. Fattorusso, O. Taglialatela-Scafati, M. Blanco-Molina, A. Macho, B.L. Fiebich, P. Bremner, M. Heinrich, M. Ballero, E. Munoz
Coumarins from Opopanax chironium. New Dihydrofuranocoumarins and Differential Induction of Apoptosis by Imperatorin and Heraclenin
J. Nat. Prod., 2004, 67, 532-536.
- M. De Angelis, G. Campiani
An efficient approach to D-theo-3-hydroxyaspartic acid for the synthesis of novel L-threo-oxazolines as selective blockers of glutamate reversed uptake
Tetr. Lett. , 2004, 45, 2355-2357.
- G. Campiani, S. Butini, C. Fattorusso, B. Catalanotti, S. Gemma, V. Nacci, E. Morelli, A. Cagnotto, I. Mereghetti, T. Mennini, M. Carli, P. Minetti, M.A. Di Cesare, D. Mastroianni, N. Scafetta, B. Galletti, M.A. Stasi, M. Castorina, L. Pacifici, M. Vertechy, S. Di Serio, O. Ghirardi, O. Tinti, P. Carminati Pyrrolo[1,3]benzothiazepine-Based Serotonin and Dopamine Receptor Antagonists. Molecular Modeling, Further Structure-Activity Relationship Studies, and Identification of Novel Atypical Antipsychotic Agents J. Med. Chem., 2004, 47, 143-157.
- Campiani G, Butini S, Fattorusso C, Trotta F, Franceschini S, De Angelis M, Nielsen KS.
Aryl piperazine derivatives for the treatment of neuropsychiatric disorders
WO 2006/072608 A2, PCT/EP2006/050001.
Hacettepe University - Department of Pharmaceutical Chemistry
- Gündüz , M. G., Çelebi, S., Kaygısız, B., Şimşek, R., Erol, K, Şafak, C., 7-Substituted hexahydroquinoline derivatives and their calcium channel modulator effects, Latin American J. Pharmacy, (in press).
- Bülbül, B., Öztürk, G. S., Vural, İ. M., Şimşek , R., Sarıoğlu , Y., Linden, A., Ülgen, M., Şafak, C., Condensed 1,4-dihydropyridines with various esters and their calcium channel antagonist activities, European J. Med. Chem. 44(5),2052-2058 (2009).
- Gündüz , M. G., Doğan, A.E., Şimşek , R., Erol, K.,Şafak, C.,Substituted 9-Aryl-1,8-acridinedione derivatives and their effects on calcium channels, J. Med. Chem.Res. 18(4), 317-325 (2009).
- Öztürk, G. S., Vural, İ. M., Gündüz , M. G., Şimşek , R., Sarıoğlu , Y., Şafak, C., Synthesis of 2-methyl-4-aryl-4,6,7,8-tetrahydro-5(1H)-quinolone derivatives and their effects on potassium channels. Arzneim. Forsch./Drug Research 58(12), 659-665 (2008).
- Takahashi D., Oyunzul L., Onoue S., Ito Y., Uchida S., Şimşek R., Gündüz M. G., Şafak C., Yamada S. Structure-Activity Relationships of Receptor Binding of 1,4-Dihydropyridine Derivatives, Biol. Pharm. Bull., 31(3), 473-479 (2008)
- Gündüz M.G., Öztürk G.S., Vural İ.M., Şimşek R., Sarıoğlu Y., Şafak C. Evaluation of Myorelaxant Activity of 7-substituted hexahydroquinoline derivatives in isolated rabbit gastric fundus, European Med Chem 43, 562-568 (2008)
- Şimşek R., Öztürk G.S., Vural I.M., Gündüz M.G., Sarıoğlu Y., Şafak C. Synthesis and calcium modulatory activity of 3-alkoxycarbonyl-4-(disubstituted aryl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives. Archiv der Pharmazie, 341(1), 55-60 (2008)
- Mielcarek J, Simşek R, Şafak C, Stefaniak H. Spectroscopic study of hexahydroquinoline derivatives--a potential group of calcium antagonists, Acta Pol Pharm., 64(6):487-490 (2007)
- Aydin, F., Şafak, C., Şimşek, R., Erol, K., Ulgen, M., Linden, A., Studies on condensed 1,4-dihydropyridine derivatives and their calcium modulatory activities, Pharmazie, 61(VIII), 655-659 (2006)
- Şimşek, R., Gündüz, M., Sirmagul, B., Şafak, C., Erol, K., Linden, A., 4-Difluoro-substituted Phenyl-5-oxo-hexahydroquinoline Derivatives and Their Effects on Calcium Channels, Arzneim. Forsch./Drug Res., 56(VII), 529-534 (2006).
- Şafak, C., Şimşek, R., Fused 1,4-Dihydropyridines as Potential Calcium Modulatory Compounds, Mini-Reviews in Medicinal Chemistry, 6, 747-755 (2006).
- Linden, A., Gündüz, M., Şimşek, R., Şafak, C., Cocrystals of Diastereoisomers of 1,4-Dihydropyridine Derivatives, Acta Crystallographica, C62, 227-230 (2006).
- Linden, A., Şimşek, R., Gündüz, M., Şafak, C., ()-Methyl and ()-ethyl 4-(2,3-difluorophenyl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, Acta Crystallographica, C61, 731-734 (2005)
- Şimşek, R., Özkan, M., Kısmetli, E., Uma, S., Şafak, C., Some Arylacridine Derivatives Possessing Potassium Channel Opening Activity, Il Farmaco, 59, 939-943 (2004).
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