Scientific Coordinator

 

National Hellenic Research Foundation
Institute of Organic and Pharmaceutical Chemistry

 

Address:

National Hellenic Research Foundation
Institute of Organic and Pharmaceutical Chemistry,
48 Vassileos Constantinou Avenue
Athens GR-11635, Greece.

Phone number:

+301 07273833

E-mail:

tcalog@eie.gr

Prof. Theodora Calogeropoulou

Curriculum vitae:

EDUCATION

B.S. in Chemistry , April 1983, National University of Athens, Athens, Greece.
Ph.D. in Organic Chemistry, July 1987, University of Iowa, Iowa City, Iowa, U.S.A.
Postdoctoral Research Associate (9/1987-10/1989) at The Scripps Research Institute, San Diego, U.S.A.
Researcher (6/1990- 8/1991) at the R&D Department of “Viochrom” S.A.
Researcher (9/1991-2002) at the Institute of Organic and Pharmaceutical Chemistry of the National Hellenic Research Foundation, Athens, Greece.
Senior Researcher (2002-to date) at the Institute of Organic and Pharmaceutical Chemistry of the National Hellenic Research Foundation, Athens, Greece.

 

PROFESSIONAL AFFILIATIONS

Member of the American Chemical Society, Member of the Greek Chemical Society, Member of the Division of Organic and Pharmaceutical Chemistry of the Greek Chemical Society

PARTICIPATION IN SCIENTIFIC COMMITTEES

Participation in the team of evaluators for Current Drugs LTD, London, U.K. (1998 to 2000), National representative of the Management Committee of COST, Action D13 “ New Molecules Towards Human Health Care” (1998-2004), Member of the expert evaluators panel for Μarie-Curie Actions (Mobility 1,5,6,7,11,12) (1999- to date), National representative of the Management Committee of COST, Action B22 “Drug Development for Parasitic Diseases”. (2004-to date), Member of the organizing committee and organizer of a number of Greek and International Symposia, Reviewer for the Journal of Organic Chemistry, Organic Letters, Journal of Medicinal Chemistry

Scientific interests:

RESEARCH INTERESTS

My current research interests are focused on the design and synthesis of biologically active molecules that act at the cellular membrane level.

In particular:

1. The design and synthesis of antiprotozoal (antileishmanial, antimalarial) and antineoplastic ether phospholipids and studies on their conformations and interactions with membranes
2. The synthesis of novel lipid molecules which will can be used as delivery systems for known drug molecules in the therapy of cancer and viral infections and in particular HIV
3. The design and synthesis of novel neurosteroids possessing anxiolytic, anticonvulsant or neuroprotective activity
4. The design and synthesis of novel benzoxazine analogues that possess antiarrhythmic or neuroprotective activity
5. Reactive oxygen species scavengers with multifunctional pharmacological profile
6. Development of synthetic methodology